Durvalumab with platinum-pemetrexed for unresectable pleural mesothelioma: survival, genomic and immunologic analyses from the phase 2 PrE0505 trial
Forde PM, et al.
Nature Medicine
January 2022
Authors and Affiliates
Patrick M. Forde 1,2,14, Valsamo Anagnostou 1,2,14, Zhuoxin Sun 3,4,14, Suzanne E. Dahlberg 5, Hedy L. Kindler 6, Noushin Niknafs 1, Thomas Purcell 7, Rafael Santana-Davila 7, Arkadiusz Z. Dudek 8, Hossein Borghaei 9, Mara Lanis 1, Zineb Belcaid 1, Kellie N. Smith 1,2, Archana Balan 1, James R. White 1, Christopher Cherry 1, I. K. Ashok Sivakumar 10, Xiaoshan M. Shao 10,11, Hok Yee Chan 1,2, Dipika Singh 1,2, Sampriti Thapa 1,2, Peter B. Illei 1,12, Drew M. Pardoll 1,2, Rachel Karchin 1,10,11, Victor E. Velculescu 1,2,11,12, Julie R. Brahmer 1,2 and Suresh S. Ramalingam 13;
1 The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA. pforde1@jhmi.edu.
2 The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, USA. pforde1@jhmi.edu.
3 The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA. vanagno1@jhmi.edu.
4 The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, USA. vanagno1@jhmi.edu.
5 ECOG-ACRIN Biostatistics Center, Boston, MA, USA.
6 Frontier Science Foundation, Boston, MA, USA.
7 Boston Children's Hospital, Boston, MA, USA.
8 University of Chicago Medicine, Chicago, IL, USA.
9 The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
10 University of Washington School of Medicine & Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
11 Metro-Minnesota Community Oncology Research Consortium, St. Louis Park, MN, USA.
12 Fox Chase Cancer Center, Philadelphia, PA, USA.
13 The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
14 Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD, USA.
15 Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.
16 Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
17 Department of Hematology and Medical Oncology, Emory University School of Medicine, Winship Cancer Institute, Atlanta, GA, USA.
# Contributed equally.