A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC
Darragh LB, et al.
Nature Cancer
November 2022
Authors and Affiliates
Laurel B Darragh 1,2, Michael M Knitz 1, Junxiao Hu 3, Eric T Clambey 4, Jennifer Backus 1, Andrew Dumit 1, Von Samedi 5, Andrew Bubak 6, Casey Greene 3,7, Timothy Waxweiler 1, Sanjana Mehrotra 5, Shilpa Bhatia 1, Jacob Gadwa 1, Thomas Bickett 1, Miles Piper 1, Kareem Fakhoury 1, Arthur Liu 8, Joshua Petit 8, Daniel Bowles 9, Ashesh Thaker 10, Kimberly Atiyeh 11, Julie Goddard 12, Robert Hoyer 9, Adrie Van Bokhoven 5, Kimberly Jordan 2, Antonio Jimeno 9, Angelo D'Alessandro 7, David Raben 1, Jessica D McDermott 9, Sana D Karam 13,14;
1 Radiation Oncology, University of Colorado Denver at Anschutz Medical Campus, Aurora, CO, USA.
2 Department of Immunology, University of Colorado Denver at Anschutz Medical Campus, Aurora, CO, USA.
3 Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Denver, Aurora, CO, USA.
4 Department of Anesthesiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
5 Department of Pathology, University of Colorado Denver at Anschutz Medical Campus, Aurora, CO, USA.
6 Department of Neurology, University of Colorado Denver at Anschutz Medical Campus, Aurora, CO, USA.
7 Department of Biochemistry and Molecular Genetics, University of Colorado Denver at Anschutz Medical Campus, Aurora, CO, USA.
8 Department of Radiation Oncology, University of Colorado, Poudre Valley Hospital, Fort Collins, CO, USA.
9 Division of Medical Oncology, University of Colorado School of Medicine, Aurora, CO, USA.
10 Department of Radiology, University of Colorado Denver at Anschutz Medical Campus, Aurora, CO, USA.
11 Department of Otolaryngology Head and Neck Surgery, University of Colorado, Memorial South Hospital, Colorado Springs, CO, USA.
12 Department of Otolaryngology Head and Neck Surgery, University of Colorado Denver at Anschutz Medical Campus, Aurora, CO, USA.
13 Radiation Oncology, University of Colorado Denver at Anschutz Medical Campus, Aurora, CO, USA. sana.karam@cuanschutz.edu.
14 Department of Immunology, University of Colorado Denver at Anschutz Medical Campus, Aurora, CO, USA. sana.karam@cuanschutz.edu.