Browse our 650+ Publications​

Latest Publications

Microbial peptides activate tumour-infiltrating lymphocytes in glioblastoma

Naghavian R, et al.
Nature
October 2023
Authors and Affiliates
Reza Naghavian 1,2, Wolfgang Faigle 1,2,3, Pietro Oldrati 1, Jian Wang 1,4, Nora C Toussaint 5,6, Yuhan Qiu 1, Gioele Medici 7, Marcel Wacker 8,9,10,11, Lena K Freudenmann 9,10,11, Pierre-Emmanuel Bonté 3, Michael Weller 12, Luca Regli 7, Sebastian Amigorena 3, Hans-Georg Rammensee 9,10,11, Juliane S Walz 8,9,10,11,13, Silvio D Brugger 14, Malte Mohme 15, Yingdong Zhao 16, Mireia Sospedra 1,2, Marian C Neidert 7,17, Roland Martin 18,19,20,21; 1 Neuroimmunology and MS Research Section (NIMS), Neurology Clinic, University of Zurich, University Hospital Zurich, Zurich, Switzerland. 2 Cellerys AG, Schlieren, Switzerland. 3 Immunity and Cancer, Institut Curie, PSL University, INSERM U932, Paris, France. 4 School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. 5 NEXUS Personalized Health Technologies, ETH Zurich, Schlieren, Switzerland. 6 Swiss Institute of Bioinformatics, Zurich, Switzerland. 7 Clinical Neuroscience Center, Department of Neurosurgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland. 8 Department of Peptide-based Immunotherapy, University of Tübingen, University Hospital Tübingen, Tübingen, Germany. 9 Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany. 10 German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), partner site Tübingen, Tübingen, Germany. 11 Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, Tübingen, Germany. 12 Laboratory of Molecular Neuro-Oncology, Department of Neurology and Clinical Neuroscience, University Hospital Zurich, University of Zurich, Zurich, Switzerland. 13 Clinical Collaboration Unit Translational Immunology, German Cancer Consortium (DKTK), Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany. 14 Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland. 15 Department of Neurosurgery, University Hospital Hamburg Eppendorf, University of Hamburg, Hamburg, Germany. 16 Computational and Systems Biology Branch, Biometric Research Program, Division of Cancer Treatment and Diagnosis, NCI, NIH, Rockville, MD, USA. 17 Department of Neurosurgery, Cantonal Hospital St. Gallen, St. Gallen, Switzerland. 18 Neuroimmunology and MS Research Section (NIMS), Neurology Clinic, University of Zurich, University Hospital Zurich, Zurich, Switzerland. roland.martin@uzh.ch. 19 Cellerys AG, Schlieren, Switzerland. roland.martin@uzh.ch. 20 Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland. roland.martin@uzh.ch. 21 Therapeutic Immune Design Unit, Center for Molecular Medicine, Department of Clinical Neurosciences, Karolinska Institutet, Stockholm, Sweden. roland.martin@uzh.ch.

Analysis of CDR3 Sequences from T-Cell Receptor β in Acute Respiratory Distress Syndrome

Hey S, et al.
Biomolecules
October 2023
Authors and Affiliates
Sara Hey 1, Dayjah Whyte 1, Minh-Chau Hoang 1, Nick Le 1, Joseph Natvig 1, Claire Wingfield 1, Charles Onyeama 2, Judie Howrylak 3, Inimary T Toby 1; 1 Department of Biology, University of Dallas, Irving, TX 75062, USA. 2 T.C Pediatrics, Bedford, TX 76021, USA. 3 Pulmonary, Allergy and Critical Care Division, Penn State Milton S. Hershey Medical Center, Hershey, PA 17033, USA.

Dynamics and survival associations of T cell receptor clusters in patients with pleural mesothelioma treated with immunotherapy

Desai AP, et al.
Journal for ImmunoTherapy of Cancer
October 2023
Authors and Affiliates
Aakash P Desai 1, Farhad Kosari 2, Maria Disselhorst 3, Jun Yin 4, Alireza Agahi 5, Tobias Peikert 6, Julia Udell 5, Sarah H Johnson 5, James Smadbeck 5, Stephen Murphy 7, Giannoula Karagouga 5, Alexa McCune 5, Janet Schaefer-Klein 5, Mitesh J Borad 8, John Cheville 7, George Vasmatzis 2, Paul Baas 3, Aaron Mansfield 9; 1 Division of Medical Oncology, Mayo Clinic, Rochester, Minnesota, USA. 2 Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, USA. 3 Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands. 4 Quantitative Health Sciences, Mayo Clinic Rochester, Rochester, Minnesota, USA. 5 Center for Individualized Medicine, Mayo Clinic Rochester, Rochester, Minnesota, USA. 6 Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USA. 7 Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA. 8 Hematology/Medical Oncology, Mayo Clinic, Phoenix, Arizona, USA. 9 Division of Medical Oncology, Mayo Clinic, Rochester, Minnesota, USA Mansfield.Aaron@mayo.edu.

Post-vaccination SARS-Cov-2 T-cell receptor repertoires in patients with multiple sclerosis and related disorders

Algu P, et al.
Multiple Sclerosis and Related Disorders
October 2023
Authors and Affiliates
Priyanka Algu 1, Natasha Hameed 2, Tracy DeAngelis 3, Joel Stern 4, Asaff Harel 5; 1 Zucker School of Medicine at Hofstra/Northwell, 173 Lawrence St., New Hyde Park, NY 11040, United States. 2 Northwell Multiple Sclerosis Center, 611 Northern Blvd, Great Neck, NY 11021, United States. 3 Neurological Associates of Long Island, 1991 Marcus Ave, New Hyde Park, NY 11042, United States. 4 Northwell Multiple Sclerosis Center, 350 Community Drive, Manhasset NY 11030, United States. 5 Northwell Multiple Sclerosis Center, 130 East 77th Street, 8 Black Hall, NY 10075, United States. Electronic address: aharel@northwell.edu.

Immunosequencing and Profiling of T Cells at the Maternal-Fetal Interface of Women with Preterm Labor and Chronic Chorioamnionitis

Miller D, et al.
Journal of Immunology
October 2023
Authors and Affiliates
Derek Miller 1,2, Roberto Romero 1,3,4, Luke Myers 5, Yi Xu 1,2, Marcia Arenas-Hernandez 1,2, Jose Galaz 1,2,6, Cinque Soto 5,7, Bogdan Done 1,2, Angelica Quiroz 1, Awoniyi O Awonuga 2, David R Bryant 2, Adi L Tarca 1,2,8,9, Nardhy Gomez-Lopez 1,2,10,9; 1 Pregnancy Research Branch, Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, U.S. Department of Health and Human Services, Bethesda, MD. 2 Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI. 3 Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI. 4 Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI. 5 Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN. 6 Division of Obstetrics and Gynecology, Faculty of Medicine, Pontificial Catholic University of Chile, Santiago, Chile. 7 Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN. 8 Department of Computer Science, Wayne State University College of Engineering, Detroit, MI. 9 Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI. 10 Department of Biochemistry, Microbiology, and Immunology, Wayne State University School of Medicine, Detroit, MI.

TRAF2/3 deficient B cells resist DNA damage-induced apoptosis via NF-κB2/XIAP/cIAP2 axis and IAP antagonist sensitizes mutant lymphomas to chemotherapeutic drugs

Vashisht M, et al.
Cell Death and Disease
October 2023
Authors and Affiliates
Monika Vashisht 1, Huaibin Ge 1, Jessy John 1, Harlie A McKelvey 1, Jingxin Chen 1, Zhangguo Chen 2, Jing H Wang 3,4; 1 UPMC Hillman Cancer Center, Division of Hematology and Oncology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 15213, USA. 2 UPMC Hillman Cancer Center, Division of Hematology and Oncology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 15213, USA. zhc90@pitt.edu. 3 UPMC Hillman Cancer Center, Division of Hematology and Oncology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 15213, USA. JHW51@pitt.edu. 4 Department of Immunology, University of Pittsburgh, Pittsburgh, PA, 15213, USA. JHW51@pitt.edu.

Persistence of ex vivo expanded tumour and pathogen specific T-cells after allogeneic stem cell transplant for myeloid malignancies (the INTACT study)

Jiang W, et al.
Leukemia
October 2023
Authors and Affiliates
Wei Jiang 1,2, Selmir Avdic 1,2, Koon H Lee 1,2,3, Janine Street 2, Gloria Castellano-González 2, Renee Simms 1,2, Leighton E Clancy 4, Richard Blennerhassett 3, Ellis Patrick 2,5, Adam S Chan 5,6, Helen M McGuire 6,7, Nadav Myers 2, Brian S Gloss 2, Melissa Gabriel 8, Caroline M Bateman 1,2,8, Ken Micklethwaite 1,2,3,9, David J Gottlieb 1,2,3, Emily Blyth 10,11,12; 1 Sydney Medical School, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia. 2 Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW, Australia. 3 Blood Transplant and Cell Therapies Program, Department of Haematology, Westmead Hospital, Westmead, NSW, Australia. 4 Research and Education Network, Western Sydney Area Health Service, Westmead, NSW, Australia. 5 School of Mathematics and Statistics, Faculty of Science, University of Sydney, Camperdown, NSW, Australia. 6 Charles Perkins Centre, The University of Sydney, Camperdown, NSW, Australia. 7 Infection, Immunity and Inflammation Theme, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia. 8 Blood Transplant and Cell Therapies Unit, The Children's Hospital at Westmead, Westmead, NSW, Australia. 9 Blood Transplant and Cell Therapies Laboratory, Institute for Pathology and Medical Research, NSW Health Pathology, Westmead, NSW, Australia. 10 Sydney Medical School, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia. emily.blyth@sydney.edu.au. 11 Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW, Australia. emily.blyth@sydney.edu.au. 12 Blood Transplant and Cell Therapies Program, Department of Haematology, Westmead Hospital, Westmead, NSW, Australia. emily.blyth@sydney.edu.au.

NAIR: Network Analysis of Immune Repertoire

Yang H, et al.
Frontiers in Immunology
October 2023
Authors and Affiliates
Hai Yang 1, Jason Cham 2, Brian Patrick Neal 1,3, Zenghua Fan 3, Tao He 4, Li Zhang 1,3,5; 1 Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, United States. 2 Department of Medicine, Scripps Green Hospital, La Jolla, CA, United States. 3 Department of Medicine, University of California San Francisco, San Francisco, CA, United States. 4 Department of Mathematics, San Francisco State University, San Francisco, CA, United States. 5 Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, United States.

Longitudinal change trend of the TCR repertoire reveals the immune response intensity of the inactivated COVID-19 vaccine

Ren C, et al.
Molecular Immunology
October 2023
Authors and Affiliates
Chengsi Ren 1, Ruili Ji 2, Yizhe Li 3, Jinyong He 4, Wei Hu 4, Xiangyun Teng 5, Jiahui Gao 4, Yue Wu 4, Jianhua Xu 6; 1 Department of Laboratory Medicine, Shunde Hospital of Guangzhou University of Chinese Medicine, Foshan, China. Electronic address: zyyrcs@163.com. 2 Department of Laboratory Medicine, Shunde Hospital of Guangzhou University of Chinese Medicine, Foshan, China. Electronic address: jiruili0302@163.com. 3 West China TianFu Hospital,Sichuan University, Chengdu, China. Electronic address: liyizhe1203@163.com. 4 Department of Laboratory Medicine, Shunde Hospital of Guangzhou University of Chinese Medicine, Foshan, China. 5 Medical Laboratory Center, Maoming Hospital of Guangzhou University of Chinese Medicine, Maoming, China; Translational Medicine Research Center, Maoming Hospital of Guangzhou University of Chinese Medicine, Maoming, China. 6 Department of Laboratory Medicine, Shunde Hospital of Guangzhou University of Chinese Medicine, Foshan, China; Medical Laboratory Center, Maoming Hospital of Guangzhou University of Chinese Medicine, Maoming, China; Translational Medicine Research Center, Maoming Hospital of Guangzhou University of Chinese Medicine, Maoming, China. Electronic address: jhxu1976@gzucm.edu.cn.

Immunophenotypic correlates of sustained MRD negativity in patients with multiple myeloma

Coffey DG, et al.
Nature Communications
October 2023
Authors and Affiliates
David G Coffey 1,2, Francesco Maura 3, Edgar Gonzalez-Kozlova 4, J Javier Diaz-Mejia 5, Ping Luo 5, Yong Zhang 6, Yuexin Xu 7, Edus H Warren 7, Travis Dawson 4, Brian Lee 4, Hui Xie 4, Eric Smith 8, Amanda Ciardiello 9, Hearn J Cho 4,10, Adeeb Rahman 4, Seunghee Kim-Schulze 4, Benjamin Diamond 3, Alexander Lesokhin 9, Dickran Kazandjian 3, Trevor J Pugh 5,11,12, Damian J Green 7, Sacha Gnjatic 4, Ola Landgren 13; 1 Division of Myeloma, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA. davidcoffey@miami.edu. 2 Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. davidcoffey@miami.edu. 3 Division of Myeloma, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA. 4 Icahn School of Medicine at Mount Sinai, New York, NY, USA. 5 Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada. 6 Office of Oncologic Diseases, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, USA. 7 Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. 8 Dana-Farber Cancer Institute, Boston, MA, USA. 9 Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. 10 Multiple Myeloma Research Foundation, Norwalk, USA. 11 Ontario Institute for Cancer Research, Toronto, ON, Canada. 12 Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada. 13 Division of Myeloma, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA. col15@miami.edu.